Blender cannot import/find ayon_core

Ah - I know what it is!

You likely added your own Blender version variant to the application settings?

You are most likely facing a a Blender “feature” where it doesn’t include PYTHONPATH passed along to it by default.

In the application settings, for your variant - expand the Arguments section.
In there add:

--python-use-system-env

As a comparison you can check the argument sections of any default pre-defined application variants for blender. Without that argument, Blender will force exclude everything from PYTHONPATH from its sys.path and hence does not include any external python libraries.

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